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Associate Professor

    WU Qiongyou

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    Post Doc. Instituteof chemistry, Academia Sinica, Taiwan (2007-2008)

    Ph.D. Collegeof Chemistry and Molecule Sciences, Wuhan University (January 2004)

    B.A. Department of chemistry, Fuyang Normal College (June 1998).

    Research Fields and Interests

    Natural product based pesticide discovery;

    Synthesis and biological evaluation of novel heterocycles.

    Financial Support

    1. National Natural Science Foundation of China (No.21472063): Target identification of pesticide pyridalyl through tandem photoaffinity labeling–bioorthogonal conjugation. 2015.01-2018.12.

    2. National Natural Science Foundation of China (No.21272091): Structure optimization, fungicidal evaluation and mechanism study of natural product sclerotiorin. 2013.01-2016.12.

    3.National Natural Science Foundation of China (No.21002038): Interaction of inhibitors with its target PPO and novel inhibitor design targeting PPO. 2011.01-2013.12.

    4. International cooperation with Syngenta: Natural product based pesticide discovery. 2008-

    Selected Publications

    1. Chen, C.; Wu, Q.Y.; * Shan, L. Y.; Zhang, B.; Verpoort, F.; G. F. Yang* Discovery of cytochrome bc1 complex inhibitors inspired by the natural product karrikinolide. RSC Adv., 2016, DOI: 10.1039/c6ra19424a.

    2. Chen,C.; Verpoort, F.*; Wu, Q. Y.* Atom-economic dehydrogenative amide synthesis viaruthenium catalysis RSC Adv., 2016, 6, 55599–55607.

    3. Chen, C.; Zhang, R.; Lin, L.; Yang, G. F.*; Wu, Q. Y.* Brønsted acid promoted one-pot synthesis of 4-aryl-3,4-dihydrocoumarins Tetrahedron, 2016, 72, 3917-3921.

    4. Cheng, H.; Wang, W. Q.; Huang, L.; Cui, P.; Wu, Q. Y.* Synthesisand biological activities of novel triazolesulfonamide derivatives containing quinolin-2-onemoiety. Chin. J. Org. Chem. 2016, 36, 1065~1072.

    5. Zuo, Y.; Wu, Q. Y.; Su, S. W.; Niu, C. W.; Xi, Z.; Yang, G. F.* Synthesis, Herbicidal activity, and QSAR of novel N‑benzothiazolylpyrimidine-2,4-diones as protoporphyrinogen oxidase inhibitors. J. Agric. Food Chem. 2016, 64, 552-562.

    6. Cheng, H.; Shen, Y. Q.; Pan, X. Y.; Hou, Y. P.; Wu, Q. Y.*;Yang, G. F.* Discovery of 1,2,4-triazole-1,3-disulfonamides as dual inhibitors of mitochondrial complex II and complex III New J. Chem., 2015, 39, 7281-7292.

    7. Wu, Q. Y.; Jiang, L. L.; Yang, S. G.; Zuo, Y.; Wang, Z. F.; Xi, Z.*; Yang, G. F.* Hexahydrophthalimide–benzothiazole hybrids as a new class of protoporphyrinogen oxidase inhibitors: synthesis, structure–activity relationship, and DFT calculations. New J. Chem., 2014, 38, 4510-4518.

    8. Wu, Q. Y.; Jiang, L. L.; Zuo, Y.; Wang, Z. F.; Xi, Z.*; Yang, G. F.* Synthesis, In Vitro Protoporphyrinogen Oxidase Inhibition, and Herbicidal Activity ofN-(Benzothiazol-5-yl)hexahydro-1H-isoindole-1,3-diones andN-(Benzothiazol-5-yl)hexahydro-1H-isoindol-1-ones. Chem Biol Drug Des. 2014, 84,431-42.

    9. Cheng, H.; Wu, Q. Y.*; Han, F.; Yang, G. F. * Efficient synthesis of 4-substituted pyrazole via microwave-promoted Suzuki cross-coupling reaction. Chinese Chemical Letters 2014,2 5, 705-709.

    10. Li, J.; Wang, Z. Y.; Wu,Q. Y.; Yang, G. F. * Design,s ynthesis and insecticidal activity of novel 1,1-dichloropropene derivatives Pest Manag Sci. 2014, doi:10.1002/ps.3827.

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