Chinese Version (中文版)
Resume
2015—present, Associate Professor, Analytical Instrumentation Center, Central China Normal University.
2013—2015, Visiting Scholar, National Institutes of Health (Advisor: Ad Bax).
2008—2015, Lecturer, Analytical Instrumentation Center, Central China Normal University.
2002—2008, Ph.D., Wuhan Institute of Physics and Mathematics of Chinese Academy of Sciences (Advisor: Maili Liu).
1998—2002, B.S., Wuhan University.
Research Fields and Interests
My research mainlyfocuses on the development and application of improved NMR methods for thestudy of Structure Biology and Metabolomics.
l Proteinstructure, dynamics and function
l Methodsfor the high-resolution characterization of structure and dynamics for largemolecular-weight biomolecules
l Metabolomicprotocols for the discovery of key biomarkers related to major disease.
Selected Publications
1. Li, F.; Grishaev,A.; Ying, J. F.; et al., Side chain conformational distributions of a small protein derived from model-free analysis of a large set of residualdipolar couplings[J]. Journal of the American Chemical Society, 2015, 137(46): 14798-147811.
2. Li, F.; Lee, J. H.; Grishaev, A.; et al., High accuracy of Karplusequations for relating three-bond Jcouplings to protein backbonetorsion angles[J]. Chem Phys Chem, 2015, 16(3): 572-578.
3. Lee, J. H.; Li, F.; Grishaev, A.; et al.,Quantitative residue-specific protein backbone torsion angle dynamics fromconcerted measurement of3Jcouplings[J]. Journal of the American Chemical Society, 2015, 137(4):1432-1435.
4. Li, F.*; Xu, Q.; Zheng, T.; et al., Metabonomic analysis of Allium macrostemon Bunge as a treatment for acute myocardial ischemia in rats[J]. Journal of Pharmaceutical and Biomedical Analysis, 2013, 88(25): 225-234.
5. Li, F.*; Zheng, T.; Xu, Q.; et al,. NMRspectroscopy and multivariate statistical analysis of metabonomic changes in Allium macrostemon Bunge extracts induced by different drying methods[J]. Analytical Methods, 2013, 5: 6219-6227.