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E—mailyinj@mail.ccnu.edu.cn

个人主页:http://scholar.google.com/citations?user=XAjy-0MAAAAJ

http://www.researcherid.com/rid/H-1832-2014 

教育与研究经历(

1981年出生于湖北洪湖,中国化学会会员、美国化学会会员。一直致力于有机荧光材料、生物传感与荧光成像方面的研究。截止目前,以通讯作者或第一作者在Nat ProtocChemChem Soc RevCoord Chem RevJ Am Chem SocBiosens BioelectronChem CommunOrg LettChem Eur JChem Asian JJ Org ChemJ Mater ChemOrg Biomol Chem等国际权威杂志发表论文一百余篇(其中IF > 10.0以上6篇,10.0 > IF > 5.0一共16篇,IF > 3.0以上论文66篇,他引次数3200多次,H指数为30),包含1Nature子刊和1Cell子刊。

2017 – Present: 教授,华中师范大学化学学院

2010 – 2017: 副教授,华中师范大学化学学院

2012 – 2013: 研究教授,韩国梨花女子大学化学与纳米科学系

2008 – 2010: 博士后, 新加坡国立大学化学系

2002 – 2007: 硕博连读, 华中师范大学化学学院

1998 – 2002: 学士, 华中师范大学化学学院

研究领域与兴趣

1. 有机荧光材料、分子探针与生物成像

1) 荧光染料的结构优化与功能调控

2) 近红外荧光探针与生物成像应用

2. 智能响应荧光传感变色材料

1) 荧光传感变色材料在生物医学工程中的应用

2) 刺激响应传感材料(光、温度、压力、蒸汽、超声等)

承担项目与课题信息

1. 湖北省自然科学基金杰出青年基金,食物链上重金属离子的动态示踪2018-2020,主持人

2. 中央高校基本科研业务费,新型近红外荧光探针的开发及其在肿瘤细胞组织成像中的应用2018-2019,主持人

3. 中央高校基本科研业务费,新型超高效除草剂喹草酮的绿色合成工艺及环境友好制剂研究,重大培育项目,2018-2018,参与人

4. 中央高校基本科研业务费,化学生物学导向的绿色农药分子设计,创新团队培育,2018-2018,参与人

5. 江南大学合成与生物胶体教育部重点实验室开放课题,功能导向型主客体体系构建粘度荧光传感器2018-2019,主持人

6. 南京工业大学材料化学工程国家重点实验室开放课题,近红外荧光材料在生物医学工程中的应用研究2018-2019,主持人

7. 长白山生物资源与功能分子教育部重点实验室(延边大学)开放课题,生物分子影像在术后感染早期诊断中的应用2017-2019,主持人

8. 国家自然科学基金面上项目:谷胱甘肽和巯基氨基酸总量时空同步检测荧光探针的开发与应用,2017-2020,主持人

9. 中央高校科研基本业务费:近红外荧光探针在术后感染早期诊断中的应用,2016-2017,主持人

10. 武汉市科技晨光计划:生物分子影像在术后感染早期诊断中的应用,2016-2018,主持人

11. 深圳市化学生物学重点实验室开放研究基金:近红外荧光探针靶向示踪体内恶性肿瘤,2016-2018,主持人

12. 国家自然科学基金青年项目:基于轮烷旋转模型构建粘度响应型荧光传感器,2015-2017,主持人

13. 中央高校科研基本业务费:基于主客体化学构建具有荧光信号特征的粘度响应型分子机器,2014-2015,主持人

14. 湖北省自然科学基金面上项目:高性能有机电子传输材料的合成与性质研究,2013-2014,主持人

15. 教育部留学回国人员科研启动基金:可开关的大环化合物的阳离子识别与释放研究,2012-2013,主持人

学术兼职

1. Chinese Chemical Letters》:青年编委(2017-2019

2. Current Smart Materials》:编委(20173月)

学术成果

1. Zhiqiang Xu, Xiaoting Huang, Xie Han, Di Wu, Bibo Zhang, Ying Tan,* Meijiao Cao, Sheng Hua Liu, Jun Yin* and Juyoung Yoon*. A Visible and Near-Infrared, Dual Channel Fluorescence-On Probe for Highly Selective, Spatiotemporal and Synchronous Tracking of Mitochondrial Glutathione. Chem 2018, 7, 1609-1628Cell旗下子刊)

2. Jinrong Zheng, Yuanzhi Shen, Zhiqiang Xu, Zhenwei Yuan, Yuanyuan He, Chen Wei, Murat Er, Jun Yin* and Haiyan Chen*. Near-infrared off-on fluorescence probe activated by NTR for in vivo hypoxia imaging. Biosens. Bioelectron. 2018, 119, 141-148

3. Guotao Liu, Weijie Chen, Zhiqiang Xu, Fengying Ye, Yingle Pan, Xiaoqiang Chen, Sheng Hua Liu, Lintao Zeng* and Jun Yin* Regulating glutathione-responsiveness of naphthalimide-based fluorescent probes by an oxidation strategy. Org. Biomol. Chem. 2018, 16, 5517-5523

4. Songyi Lee, Jun Li, Xin Zhou,* Jun Yin* and Juyoung Yoon*. Recent Progress on the Development of Glutathione (GSH) Selective Fluorescent and Colorimetric Probes. Coord. Chem. Rev. 2018, 366, 29-68

5. Xie Han, Dongyang Li, Xiaoxie Ma, Sheng Hua Liu, and Jun Yin*. Photoactivatable Fluorescence Enhanced Behaviour of Benzo[c][1,2,5]oxadiazole-dressing Tetraphenylethene. New J. Chem. 2018, 42, 6609-6612

6. Jianhua Chen, Dongyang Li, Weijie Chi, Guotao Liu, Sheng Hua Liu, Xiaogang Liu,* Chun Zhang* and Jun Yin*. A Highly Reversible Mechanochromic Difluorobenzothiadiazole Dye with Near-Infrared Emission. Chem. Eur. J. 2018, 24, 3671-3676 (Hot Paper)

7. Di Wu, Liyan Chen, Woolin Lee, Gyeongju Ko, Jun Yin* and Juyoung Yoon*. Recent progress in the development of organic dye based near-infrared fluorescence probes for metal ions. Coord. Chem. Rev. 2018, 354, 74-97

8. Zhiqiang Xu, Haojie Ge, Xie Han, Sheng Hua Liu, Xiang-Gao Meng* and Jun Yin*. Self-recognition Behavior of Novel Frameworks Containing Both Urea and Carboxylate Anion. Tetrahedron 2017, 73, 6386-6391

9. Xie Han, Bibo Zhang, Jianhua Chen, Ying Tan* Chunyan Tan, Sheng Hua Liu, Xiaogang Liu,* and Jun Yin*. The Optical Behaviors of Fluorophore-dressing Tetraphenylethenes in Aggregation State and Their Bioimaging in Tumor Cells. J. Mater. Chem. B 2017, 5, 5096-5100

10. Guotao Liu, Dan Liu, Xie Han, Xiaole Sheng, Zhiqiang Xu, Sheng Hua Liu, Lintao Zeng* and Jun Yin*. A hemicyanine-based colorimetric and ratiometric fluorescent probe for selective detection of cysteine and bioimaging in living cell. Talanta 2017, 170, 406-412

11. Xie Han, Guotao Liu, Sheng Hua Liu and Jun Yin*. Synthesis of rotaxanes and catenanes using imine clipping reaction. Org. Biomol. Chem. 2016, 14, 10331-10351. (Cover Paper)

12. Meijiao Cao, Haiyan Chen,* Dan Chen, Zhiqiang Xu, Sheng Hua Liu, Xiaoqiang Chen,* and Jun Yin*. Naphthalimide-based fluorescent probe for selectively and specifically detecting glutathione in lysosome of living cells. Chem. Commun. 2016, 52, 721-724

13. Li Dai, Di Wu, Qinglong Qiao, Wenting Yin, Jun Yin* and Zhaochao Xu*. A Naphthalimide-based fluorescent sensor for halogenated solvents. Chem. Commun. 2016, 52, 2095-2098

14. Di Wu, Yufeng Zhang, Jing Zhang, Sheng Hua Liu,* and Jun Yin*. Dibenzocarbazolediimides: Synthesis, Solid Structure, Self-Assembly Behavior, and Optoelectronic Properties. Chem. Asian J. 2015, 10, 1344-1353

15. Fang Hu, Meijiao Cao, Xiang Ma, Sheng Hua Liu* and Jun Yin*. The visible light–dependent photocyclization: design, synthesis and properties of a cyanine-based dithienylethene. J. Org. Chem. 2015, 80, 7830-7835

16. Yufeng Zhang, Haiyan Chen,* Dan Chen, Di Wu, Xiaoqiang Chen, Sheng Hua Liu* and Jun Yin*. A fluorescent turn-on H2S-responsive probe: design, synthesis and application. Org. Biomol. Chem. 2015, 13, 9760-9766

17. Di Wu, Zhao Chen, Yufeng Zhang, Jing Zhang, Sheng Hua Liu,* and Jun Yin*. Imides Modified Dinaphtho[1,2-b:2′,1′-d]thiophene and Dinaphtho[1,2-b:2′,1′-d]thiophene 13,13-dioxide: Synthesis and Optoelectronic Properties. J. Org. Chem. 2015, 80, 8443−8448

18. Xie Han, Meijiao Cao, Zhiqiang Xu, Di Wu, Zhao Chen, Anxin Wu, Sheng Hua Liu, and Jun Yin*. Aggregation-induced emission behavior of pH-controlled molecular shuttle based on tetraphenylethene moiety. Org. Biomol. Chem. 2015, 13, 9767-9774

19. Dayoung Lee, Gyoungmi Kim, Jun Yin,* and Juyoung Yoon*. Aryl-thioether labelling nitrobenzothiadiazole for selective detection of cysteine and homocysteine. Chem. Commun. 2015, 51, 6518-6520

20. Di Wu, Hua Zhang, Sheng Hua Liu,* and Jun Yin*. Naphthalimide Based Triptycenes: Synthesis and Optoelectronic Properties. Chem. Asian J. 2015, 10, 602-607

21. Zhao Chen, Jing Zhang, Min Song, Jun Yin,* Guang-Ao Yu and Sheng Hua Liu*. A novel fluorene-based aggregation-induced emission (AIE)-active gold (I) complex with crystallization-induced emission enhancement (CIEE) and reversible mechanochromism characteristics. Chem. Commun. 2015, 51, 326-329

22. Jun Yin, Ying Hu and Juyoung Yoon*. Fluorescent probes and bioimaging: alkali metals, alkaline earth metals and pH. Chem. Soc. Rev. 2015, 44, 4619-4644

23. Jun Yin, Younghee Kwon, Dabin Kim, Dayoung Lee, Gyoungmi Kim, Ying Hu, Ji-Hwan Ryu,* and Juyoung Yoon*. Preparation of a cyanine-based fluorescent probe for highly selective detection of glutathione and its use in living cells and tissues of mouse. Nat. Protoc. 2015, 10, 1742-1754Nature旗下子刊)

24. Jun Yin, Younghee Kwon, Dabin Kim, Dayoung Lee, Gyoungmi Kim, Ying Hu, Ji-Hwan Ryu,* and Juyoung Yoon*. A Cyanine Based Fluorescence Probe for Highly Selective Detection of Glutathione in Cell Cultures and Live Mice Tissues. J. Am. Chem. Soc. 2014, 136, 5351-5358

25. Zhao Chen, Di Wu, Xie Han, Jinhua Liang, Jun Yin,* Guang-Ao Yu, and Sheng Hua Liu*. A novel fluorene-based gold (Ι) complex with aggregate fluorescence change: a single-component white light-emitting luminophor. Chem. Commun. 2014, 50, 11033-11035

26. Xin Zhang, Jun Yin, and Juyoung Yoon*. Recent Advances in Development of Chiral Fluorescent and Colorimetric Sensors. Chem. Rev. 2014, 114, 4918−4959

27. Guoxing Liu, Ziyong Li, Di Wu, Wen Xue, Tingting Li, Sheng Hua Liu* and Jun Yin*. Dendritic [2]Rotaxanes: Synthesis, Characterization and Properties. J. Org. Chem. 2014, 79, 643-652

28. Ziyong Li, Guoxing Liu, Wen Xue, Di Wu, Ying-Wei Yang, Jishan Wu, Sheng Hua Liu,* Juyoung Yoon,* Jun Yin*. Construction of Hetero[n]rotaxanes by Use of Polyfunctional Rotaxane Frameworks. J. Org. Chem. 2013, 78, 11560−11570

29. Di Wu, Hua Zhang, Jinhua Liang, Haojie Ge, Chunyan Chi, Jishan Wu, Sheng Hua Liu,* Jun Yin*. Functionalized Coronenes: Synthesis, Solid Structure and Properties. J. Org. Chem. 2012, 77, 11319-11324

30. Ziyong Li, Wenju Liu, Jishan Wu, Sheng Hua Liu, Jun Yin*. Synthesis of [2]Catenanes by Template-Directed Clipping Approach. J. Org. Chem. 2012, 77, 7129-7135

获奖及荣誉信息

1. 指导的本科生马晓媟获得湖北省第十一届大学生化学(化工)学术创新成果二等奖,2018

2. 获得2017年度中国化学会《中国化学快报》优秀审稿人称号,2018

3. 指导的硕士研究生刘国涛获得国家奖学金,2017

4. 中国化学会第十八届大环化学暨第十届超分子化学学术讨论会,墙报奖,2016

5. 指导的硕士研究生盛晓乐获得国家奖学金,2016

6. 获得IKA学者奖,2015

7. 指导的硕士研究生曹梅娇获得国家奖学金,2015

8. 指导的硕士研究生张宇峰获得精诚励志奖学金,2015

9. 中国化学会第十二届全国分析化学年会,墙报奖,2015

10. 中国化学会第十七届大环化学暨第九届超分子化学学术讨论会,墙报奖,2014

11. 获得优秀班主任称号,2014

12. 指导的博士研究生李自永获得国家奖学金,2013

13. 2010年:湖北省自然科学二等奖:功能金属有机化合物的合成及性能研究,2010