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教育经历:

2001/09-2005/07 华中农业大学学士

2005/09-2007/07 华中科技大学硕士(李涛教授)

2012/09-2013/11 武汉大学 博士(洪学传教授/邓子新院士)

2013/11-2015/04 斯坦福大学/武汉大学联合培养博士(国家留学基金委资助)

2015/08-2016/08 斯坦福大学医学院分子影像中心 博士后 (程震教授、LeiXing教授)

工作经历:

2009/01-2011/03 中国科学院上海药物所科研助理(杨财广教授课题组)

2017/01-至今 华中师范大学 化学学院 研究员

研究领域:

1.高组织穿透能力和高时空分辨率的新型近红外二区荧光小分子探针的设计,合成及其在生物大分子活体动态变化监测中的研究;

2.智能型、反应型和多功能高特异性荧光探针的设计,合成及其在疾病相关的生物分子动态监测中的研究;

3.基于生物正交化学策略及点击化学策略构建多功能荧光探针及性能研究。

联系邮箱

sunyaogbasp@126.com

代表性工作:

1. Ruiping Zhang, Zhenjun Wang, Liying Xu, Yuling Xu, Yi Lin, Ying Zhang, Yao Sun*, Guangfu Yang. Rational Design of a Multifunctional Molecular Dye with Single Dose and Laser for Efficiency NIR-II Fluorescence/Photoacoustic Imaging Guided Photothermal Therapy. Anal. Chem., 2019, DOI: 10.1021/acs.analchem.9b03152.

2. Yue Sun, Feng Ding, Zhao Chen, Ruiping Zhang, Chonglu Li, Yuling Xu, Yi Zhang, Ruidong Ni, Xiaopeng Li, Guangfu Yang, Yao Sun*, Peter J. Stang*,. Melanin-dot-meduated delivery of metallacycle for NIR-II/photoacoustic dual-modal imaging0guided chemo-photothermal synergistic therapy. Proc. Natl. Acad. Sci. USA, 2019, 116, 16729.

3. Ruiping Zhang, Yuling Xu, Yi Zhang, Hyeong Seok Kim, Amit Sharma, Jing Gao, Guangfu Yang, Jong Seung Kim*, Yao Sun*. Rational design of a multifunctional molecular dye for dual-modal NIR-II/photoacoustic imaging and photothermal therapy. Chem. Sci, 2019, doi.org/10.1039/C9SC03504D.

4. Feng Ding, Zhao Chen, Won Young Kim, Amit Sharma, Chonglu Li, Qingying Ouyang, Hua Zhu, Guangfu Yang, Yao Sun*, Jong Seung Kim*. A nano-cocktail of an NIR-II emissive fluorohore and organoplatinum(II) metallacycle for efficient cancer imaging and therapy. Chem. Sci, 2019, 10, 7023.

5. Ruiping Zhang, Xiaoya Chen, Zhongyue Sun, Sen Chen, Jing Gao, Yao Sun*, Haibing Li*. Switchable Nanochannel Biosensor for H2S Detection Based on an Azide Reduction Reaction Controlled BSA Aggregation. Anal. Chem, 2019, 91, 6149.

6. Feng Ding, Yong Fan, Yao Sun*, Fan Zhang*. Beyond 1000 nm Emission Wavelength: Recent Advances in Organic and Inorganic Emitters for Deep-Tissue Molecular Imaging. Adv. Healthcare. Mater, 2019, 8, 1900260.

7. Yao Sun, Sen Chen, Xiaoya Chen, Yuling Xu, Siyun Zhang, Qingying Ouyang, Guangfu Yang*, Haibing Li*. A highly selective and recyclable NO-responsive nanochannel based on a spiroring opening-closing reaction strategy. Nat. Commun, 2019, 10, 1323.

8. Yue Sun, Feng Ding, Zhixuan Zhou, Chonglu Li, Maoping Pu, Yuling Xu, Yibei Zhan, Xiaoju Lu, Haibing Li*, Guangfu Yang*, Yao Sun*, Peter J. Stang*. Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy. Proc. Natl. Acad. Sci. USA, 2019, 116, 1968.

9. Feng Ding, Chonglu Li, Yuling Xu, Jiaxin Li, Haibing Li, Guangfu Yang*, Yao Sun*. PEGylation Regulates Self-Assembled Small-Molecule Dye-Based Probes from Single Molecule to Nanoparticle Size for Multifunctional NIR-II Bioimaging. Adv. Healthcare. Mater, 2018, 7, 1800973.

10. Feng Ding, Yibei Zhan, Xiaoju Lu, Yao Sun*. Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging. Chem. Sci, 2018, 9, 4370.

11. Huan Pang, Pingping Xu, Chonglu Li, Yibei Zhan, Zengyuan Zhang, Wansu Zhang, GuangFu Yang, Yao Sun,* Haibing Li. A Photo-Responsive Macroscopic Switch Constructed by Chiral Azo-Calix[4]arene Functionalized Silicon Surface. Chem. Commun, 2018, 54, 2978.

12. Yao Sun, Xiaodong Zeng, Yuling Xiao, Changhao Liu, Hua Zhu, Hui Zhou, Ziyang Chen, Fuchun Xu, Jule Wang, Mengyue Zhu, Junzhu Wu, Hong Zhang, Zixin Deng, Zhen Cheng,* Xuechuan Hong.* Novel Dual-Functional Near-Infrared II Fluorescence and PET Probe for Tumor Delineation and Imaging-Guided Surgery. Chem. Sci, 2018, 9, 2092.

13. Yao Sun, Mingmin Ding, Xiaodong Zeng, Yuling Xiao, Huaping Wu, Hui Zhou, Bingbing Ding, Chunrong Qu, Wei Hou, AGA Er-bu, Yejun Zhang, Zhen Cheng, Xuechuan Hong.* Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery. Chem. Sci, 2017, 8, 3489.

14. Yao Sun, Chunrong Qu, Hao Chen, Maomao He, Chu Tang, Kangquan Shou, Suhyun Hong, Meng Yang, Yuxin Jiang, Bingbing Ding, Yuling Xiao, Lei Xing, Xuechuan Hong,* Zhen Cheng.* Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II imaging of cancer. Chem. Sci, 2016, 7, 6203.

15. Yao Sun, Xiaowei Ma, Kai Cheng, Biying Wu, Jianli Duan, Hao Chen, Lihong Bu, Ruiping Zhang, Xianming Hu, Zixin Deng, Lei Xing, Xuechuan Hong,* Zhen Cheng.* Strained Cyclooctyne as a Novel Molecular Platform for Construction of Multimodal Imaging Probes. Angew. Chem. Int. Ed., 2015, 54, 5981. (Hot paper