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邮箱:caimeng2016@mail.ccnu.edu.cn

电话:18271899276

华中师范大学化学学院,湖北省武汉市洪山区珞喻路152号

个人信息

出生日期: 1987.11 ; 籍贯:湖北

专业兴趣:药物的作用机制及靶标蛋白功能研究,活性小分子的高通量,筛选药物的抗药性风险及抗性机制研究

教育经历

· 2016.08-至今:师资博士后

· 2014.11-2016.02:国家公派联合培养博士研究生,Dr. Brett Tyler课题组,植物与植物病理学专业,基因组与生物信息学研究中心,俄勒冈州立大学

· 2009.09-2016.06博士,刘西莉教授课题组,杀菌剂药理学及抗药性方向,植物保护学院,中国农业大学

· 2005.09-2009.07:学士,农学与生物技术学院,中国农业大学

承担项目与课题信息

· 国家自然科学基金青年基金卵菌PDHc E1蛋白表达体系的建立及相关抑制剂的设计合成与筛选,31701820,25万,2018.01-2020.12,主持。

· 湖北省自然科学基金:小麦赤霉病菌PDHc E1表达体系的建立及相关抑制剂的筛选与相互作用研究,2017CFB232,5万,2017.01-2018.12,主持。

· 高校基本科研业务费针对重要水稻病害的新型抑制剂筛选,CCNU16A05053,8万,2016.10-2018.10,主持。

学术成果

· Meng Cai, Dong Lin, Lei Chen, Yang Bi, Lu Xiao, Xi-li Liu. M233I Mutation in the β-Tubulin of Botrytis cinerea Confers Resistance to Zoxamide. Scientific Reports, 2015.

· Meng Cai, Jianqiang Miao, Song Xi, Dong Lin, Yang Bi, Lei Chen, Brett M. Tyler, Xili Liu. C239S mutation in the β-tubulin of Phytophthora sojae confers resistance to zoxamide. Frontiers in Microbiology, 2015.

· Jianqiang Miao, Meng Cai, Xue Dong, Li Liu, Dong Lin, Can Zhang, Zhili Pang, Xili Liu. Resistance assessment for oxathiapiprolin in Phytophthora capsici and the detection of a point mutation (G769W) in PcORP1 that confers resistance. Frontiers in Microbiology, 2015.

· Yang Bi, Lei Chen, Meng Cai, Shusheng Zhu, Zhili Pang, Xili Liu. Two Non-target Recessive Genes Confer Resistance to the Anti-Oomycete Microtubule Inhibitor Zoxamide in Phytophthora capsici. Plos One, 2014.

· Lei Chen, Shusheng Zhu, Xiaohong Lu, Zhili Pang, Meng Cai, Xili Liu. Assessing the risk that Phytophthora melonis can develop a point mutation (V1109L) in CesA3 conferring resistance to carboxylic acid amide fungicides. Plos One. 2012.

· X.X.Ni, B.T.Li, M. Cai, and X. L. Liu. First Report of Brown Ring Patch Caused by Waitea circinata var circinata on Agrostis stolonifera and Poa pratensis in China. Plant Disease.2012.

· Deng Weiping, Mei Xinyue, Yang Min, Chen Lei, Bi Yang, Cai Meng, Wang Haiyan, A Puqian,He Xiahong, Zhu Shusheng. Correlation between sensitivity to zoxamide and the mutation of β-tubulin amino acid of Colletotrichum gloeosporioides and two Phytophthora spp.isolates. Chinese Journal of Pesticide Science, 2012.

· Yang Bi, Xiaolan Cui, Xiaohong Lu, Meng Cai, Xili Liu, and Jianjun J. Hao. Baseline Sensitivity of Natural Population and Resistance of Mutants in Phytophthora capsici to Zoxamide. Phytopathology, 2011.

· Meng Cai, Dong Lin, Lei Chen, Xi-li Liu. Comparative study of resistance mechanisms to zoxamide and carbendazim in Botrytis cinerea. Fungal Genetics Conference, 2015.

· Chen Chen, Jingpeng Shao, Meng Cai, Xi-li Liu. Quorum sensing of the zoospores in Phytophthora capsici.Oomycete Molecular Genetics Network, 2015.

· Meng Cai, Botao Li, Dong Lin, Xili Liu. Risk Assessment and Resistance Molecular Mechanism of Magnaporthe oryzae to Three DMIs. The American Phytopathological Society, 2014.

· M. Cai, L. Chen. Characterization of genotype and phenotypes of B. cinerea isolates to zoxamide and carbendazim.10th International Congress of Plant Pathology. 2013

· Meng Cai. The resistance evolution of Phytophthora sojae to flumorph via a gradually accumulated process. Oomycete Molecular Genetics Network (OMGN) Meeting. 2012.

· 刘西莉, 蔡萌, 林东, 陈磊, 毕扬, 宋晰, 李健强, 刘鹏飞. 一种鉴定番茄灰霉病菌对苯酰菌胺抗药性的分子检测方法: 中国农业大学,CN103789409 B. 2015.

· 刘西莉, 蔡萌, 林东, 陈磊, 毕扬, 宋晰, 李健强, 刘鹏飞. 一种快速鉴定大豆疫霉对烯酰吗啉抗药性的方法及专用引物对: 中国,201610220525.5. 2016.

· 刘西莉, 陈磊, 朱书生, 卢晓红, 庞智黎, 蔡萌, 毕扬. 一种快速鉴定瓜类疫霉对CAA类杀菌剂抗药性的方法及专用引物: 中国,CN102876773A. 2013.

· 刘西莉, 卢晓红, 庞智黎, 毕扬, 王治文, 蔡萌, 陈磊. 一种鉴定辣椒疫霉CesA3基因核苷酸点突变及其对CAA类杀菌剂抗药性的方法: 中国,CN102776290A. 2012.